Carpal Tunnel Syndrome | bisphosphonates cause carpal tunnel syndrome

By: Nathan Wei

Here’s another complication of taking bisphosphonate drugs for osteoporosis… next Do Bisphosphonates Increase Risk of Carpal Tunnel Syndrome? Lara Pullen writing in the Rheumatologist reported increasingly, postmenopausal women are prescribed bisphosphonates in an effort to prevent osteoporotic fractures. The increased prevalence of bisphosphonate use likely reflects both demographic trends toward an older female population, as well as concerns about the safety of an alternative treatment for osteoporosis: hormone replacement therapy. Unfortunately, bisphosphonates are not without risk. In 2008, the FDA issued an alert that highlighted the association between oral bisphosphonates and incapacitating bone, joint and/or musculoskeletal pain. In 2015, the FDA issued yet another alert: warning that the use of bisphosphonates is associated with an increased risk for developing osteonecrosis of the jaw. Researchers have also noted that patients taking bisphosphonates experience an increased risk for arthritis and corresponding arthralgia. Now, investigators report that postmenopausal women who use bisphosphonates are also at increased risk for carpal tunnel syndrome. Comment: what a list of side effects.

These drugs might be useful but be careful.

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